Anisomycin from Streptomyces griseolus
Anisomycin
CAS: 22862-76-6
Molecular Formula: C14H19NO4
Anisomycin from Streptomyces griseolus - Names and Identifiers
Anisomycin from Streptomyces griseolus - Physico-chemical Properties
| Molecular Formula | C14H19NO4 |
| Molar Mass | 265.3 |
| Density | 1.1356 (rough estimate) |
| Melting Point | 140-141 C |
| Boling Point | 408.52°C (rough estimate) |
| Flash Point | 87℃ |
| Water Solubility | Soluble in water at 2 mg/ml, in DMSO at 20mg/ml, and in methanol at 20mg/ml |
| Solubility | methanol: 20 mg/mL, clear, colorless to faintly yellow |
| Appearance | morphological solid |
| Color | white |
| Merck | 14,670 |
| BRN | 20705 |
| pKa | 7.9(at 25℃) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Sensitive to heat and easy to absorb moisture |
| Refractive Index | 1.5230 (estimate) |
| MDL | MFCD00077650 |
| Physical and Chemical Properties | Bioactive Anisomycin (Flagecidin, Wuningmeisu C) is an antibacterial antibiotic extracted from Streptomyces griseolus, which inhibits protein synthesis and is also a JNK activator. Anisomycin can promote autophagy and apoptosis. |
| Use | Use inhibitor of protein synthesis. Causing apoptosis of PC12 cells. |
Anisomycin from Streptomyces griseolus - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 3462 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | BZ9800000 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29419090 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 orl-rat: 72 mg/kg ANTCAO 5,490,55 |
Anisomycin from Streptomyces griseolus - Reference
| Reference Show more | 1. [IF=5.555] Bai Yu et al."Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells."Front Endocrinol. 2021 Jun;0:597 |
Anisomycin from Streptomyces griseolus - Nature
| maximum wavelength (& lambda;max) | 283nm(EtOH)(lit.) |
Last Update：2024-04-09 15:16:20
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Product Name: Anisomycin Visit Supplier Webpage Request for quotationCAS: 22862-76-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Anisomycin Visit Supplier Webpage Request for quotationCAS: 22862-76-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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